Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bisphenol B 对雌激素受体具有结合亲和力。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 g | ¥ 247 | 现货 | ||
2 g | ¥ 349 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 99 | 现货 |
产品描述 | Bisphenol B has a binding affinity for estrogen receptors. |
体内活性 | Exposured to Bisphenol B?for chronic duration can induce structural changes in testicular tissue and endocrine alterations in the male reproductive system[1]. |
动物实验 | Male rats (22 day old) were exposed to water containing 0.1% ethanol for control or different concentrations of BPA and its analogues BPB, BPF and BPS (5, 25 and 50?μg/L) in drinking water for 48 weeks. Results of the present study showed a significant alteration in the gonadosomatic index (GSI) and relative reproductive organs weights. Oxidative stress in the testis was significantly elevated while sperm motility, Daily sperm production (DSP) and number of sperm in epididymis were reduced. Plasma testosterone, LH and FSH concentrations were reduced and estradiol levels were high in 50?μg/L exposed group[1]. |
分子量 | 242.31 |
分子式 | C16H18O2 |
CAS No. | 77-40-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (92.85 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 4.1269 mL | 20.6347 mL | 41.2694 mL | 103.1736 mL |
5 mM | 0.8254 mL | 4.1269 mL | 8.2539 mL | 20.6347 mL | |
10 mM | 0.4127 mL | 2.0635 mL | 4.1269 mL | 10.3174 mL | |
20 mM | 0.2063 mL | 1.0317 mL | 2.0635 mL | 5.1587 mL | |
50 mM | 0.0825 mL | 0.4127 mL | 0.8254 mL | 2.0635 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Bisphenol B 77-40-7 Endocrinology/Hormones Estrogen Receptor/ERR Inhibitor inhibitor inhibit